Study Finds Oral THC Safely and Effectively Addresses PTSD Symptoms

The administration of oral THC mitigates symptoms of post-traumatic stress syndrome (PTSD), according to clinical trial data published online ahead of print in the journal Clinical Drug Investigation.


Investigators at the Hebrew University Medical Center in Jerusalem assessed the safety and efficacy of oral THC as an adjunct treatment in ten subjects with chronic PTSD.

PTSD (Post Traumatic Stress Disorder) is a psychological condition that afflicts 7–8 percent of the population. It hits people who have been exposed to highly stressful situations in which their “fight or flight” response has been activated: rape survivors, war veterans, policemen for example.

People with PTSD can be highly irritable and suffer from insomnia, nightmares, and the inability to sustain deep relationships.

For the study, ten outpatients with chronic PTSD, on stable medication, received 5 mg of delta-9-THC twice a day as add-on treatment.

Researchers reported: “The intervention caused a statistically significant improvement in global symptom severity, sleep quality, frequency of nightmares, and PTSD hyperarousal symptoms.”

They concluded, “Orally absorbable delta-9-THC was safe and well tolerated by patients with chronic PTSD.”

Last month, a similar study found marijuana to be associated with reductions in PTSD symptoms in some patients.

And only last week we learned Arizona is likely to become the twelfth State to provide PTSD patients access to medical marijuana and with such high rates of war veterans committing suicide (22 a day), let’s hope sensible legislation will be able to bring this number down.